MHRA Drug Safety Update: Prescribing Medicines in Renal Impairment

The MHRA Drug Safety Update has issued advise on prescribing medicines in renal impairment to ensure that the appropriate estimate of renal function is used to avoid the risk of adverse drug reactions

For most patients and most medicines, estimated Glomerular Filtration Rate (eGFR) is an appropriate measure of renal function for determining dosage adjustments in renal impairment; however, in some circumstances, the Cockcroft-Gault formula should be used to calculate creatinine clearance (CrCl).

The full information can be found here.

For advice on prescribing in renal impairment please contact your ward pharmacist or Speeds Medicines Information on 0843 506 5554

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